Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking
Apurinic/apyrimidinic endonuclease 1 (APE1) is an enzyme responsible for the initial step in the base excision repair pathway and is known to be a potential drug target for treating cancers, because its expression is associated with resistance to DNA-damaging anticancer agents. Although several inhi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korea Genome Organization
2017-12-01
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| Series: | Genomics & Informatics |
| Subjects: | |
| Online Access: | http://genominfo.org/upload/pdf/gi-2017-15-4-147.pdf |