Sensitive detection of antigen-specific T-cells using bead-bound antigen for in vitro re-stimulation

Reliable and sensitive detection of antigen specific cells is essential in several fields of research, whether it concerns monitoring responses to infectious agents or exploring the auto-antigen repertoire in autoimmune diseases. Identification of these cells is however difficult, especially when th...

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Bibliographic Details
Main Authors: Mattias Bronge, Andreas Kaiser, Claudia Carvalho-Queiroz, Ola B. Nilsson, Sabrina Ruhrmann, Erik Holmgren, Tomas Olsson, Guro Gafvelin, Hans Grönlund
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:MethodsX
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016119301797