Phylogenetic comparison and splice site conservation of eukaryotic U1 snRNP-specific U1-70K gene family

Abstract Eukaryotic cells can expand their coding ability by using their splicing machinery, spliceosome, to process precursor mRNA (pre-mRNA) into mature messenger RNA. The mega-macromolecular spliceosome contains multiple subcomplexes, referred to as small nuclear ribonucleoproteins (snRNPs). Amon...

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Bibliographic Details
Main Authors: Tao Fan, Yu-Zhen Zhao, Jing-Fang Yang, Qin-Lai Liu, Yuan Tian, Das Debatosh, Ying-Gao Liu, Jianhua Zhang, Chen Chen, Mo-Xian Chen, Shao-Ming Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91693-3