Alarmins in Osteoporosis, RAGE, IL-1, and IL-33 Pathways: A Literature Review
Alarmins are endogenous mediators released by cells following insults or cell death to alert the host’s innate immune system of a situation of danger or harm. Many of these, such as high-mobility group box-1 and 2 (HMGB1, HMGB2) and S100 (calgranulin proteins), act through RAGE (receptor f...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
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Series: | Medicina |
Subjects: | |
Online Access: | https://www.mdpi.com/1010-660X/56/3/138 |