Sequence-based <it>in silico</it> analysis of well studied Hepatitis C Virus epitopes and their variants in other genotypes (particularly genotype 5a) against South African human leukocyte antigen backgrounds

<p>Abstract</p> <p>Background</p> <p>Host genetics influence the outcome of HCV disease. HCV is also highly mutable and escapes host immunity. HCV genotypes are geographically distributed and HCV subtypes have been shown to have distinct repertoires of HLA-restricted vi...

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Bibliographic Details
Main Authors: Prabdial-Sing Nishi, Puren Adrian J, Bowyer Sheila M
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Immunology
Subjects:
HCV
HLA
Online Access:http://www.biomedcentral.com/1471-2172/13/67