Computer-aided Design of Chalcone Derivatives as Lead Compounds Targeting Acetylcholinesterase

Computer-aided Design of Chalcone Derivatives as Lead Compounds Targeting Acetylcholinesterase

One of well-established biological activities for chalcone derivatives is as acetylcholinesterase inhibitors, which can be developed for the therapy of Alzheimer’s disease. Assisted byretrospectively validated structure-based virtual screening (SBVS) protocol to identify potent acetylcholinesterase...

Full description

Bibliographic Details
Main Authors: Florentinus Dika Octa Riswanto, Maywan Hariono, Sri Hartati Yuliani, Enade Perdana Istyastono
Format: Article
Language:English
Published: Universitas Gadjah Mada 2017-04-01
Series:Indonesian Journal of Pharmacy
Subjects:
Computer-aided drug design
virtual screening
chalcone derivatives
acetylcholinesterase
Alzheimer’s disease
Online Access:http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1182/811

Internet

http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1182/811

Similar Items