Humanized Mouse Models for the Advancement of Innate Lymphoid Cell-Based Cancer Immunotherapies

Humanized Mouse Models for the Advancement of Innate Lymphoid Cell-Based Cancer Immunotherapies

Innate lymphoid cells (ILCs) are a branch of the immune system that consists of diverse circulating and tissue-resident cells, which carry out functions including homeostasis and antitumor immunity. The development and behavior of human natural killer (NK) cells and other ILCs in the context of canc...

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Bibliographic Details
Main Authors: Nina B. Horowitz, Imran Mohammad, Uriel Y. Moreno-Nieves, Ievgen Koliesnik, Quan Tran, John B. Sunwoo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
humanized mice
innate lymphocyte cells
natural killer cell
cancer immunotherapy
oncoimmunology
PDX models
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.648580/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.648580/full

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