Optimal Design for Estimating Parameters of the 4-Parameter Hill Model
Many drug concentration-effect relationships are described by nonlinear sigmoid models. The 4-parameter Hill model, which belongs to this class, is commonly used. An experimental design is essential to accurately estimate the parameters of the model. In this report we investigate properties of D-opt...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2003-07-01
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| Series: | Dose-Response |
| Online Access: | https://doi.org/10.1080/15401420390249925 |