Heterozygous HTRA1 missense mutation in CADASIL-like family disease

The aim of this study was to find related pathogenic genes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy in (CADASIL)-like patients. The direct sequencing and high-throughput multiplex polymerase chain reaction (PCR) was performed to screen for related...

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Bibliographic Details
Main Authors: Xiaowei Wu, Changxin Li, Jinming Mao, Ling Li, Yan Liu, Yao Hou
Format: Article
Published: Associação Brasileira de Divulgação Científica 2018-03-01
Series:Brazilian Journal of Medical and Biological Research
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000500602&lng=en&tlng=en