TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation

TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation

Cellular reprogramming proceeds in a stepwise pathway initiated by binding and transcription of pluripotency factors followed by genome-wide epigenetic changes. Priming events, such as erasure of DNA methylation and chromatin remodeling determines the success of pluripotency acquisition later. There...

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Bibliographic Details
Main Authors: Marta Klimczak, Patrycja Czerwińska, Sylwia Mazurek, Barbara Sozańska, Przemysław Biecek, Andrzej Mackiewicz, Maciej Wiznerowicz
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Stem Cell Research
Subjects:
TRIM28
KAP1
iPS cells
Pluripotency
Epigenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117301368

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http://www.sciencedirect.com/science/article/pii/S1873506117301368

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