Visualization of translocons in Yersinia type III protein secretion machines during host cell infection.

Type III secretion systems (T3SSs) are essential virulence factors of numerous bacterial pathogens. Upon host cell contact the T3SS machinery-also named injectisome-assembles a pore complex/translocon within host cell membranes that serves as an entry gate for the bacterial effectors. Whether and ho...

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Bibliographic Details
Main Authors: Theresa Nauth, Franziska Huschka, Michaela Schweizer, Jens B Bosse, Andreas Diepold, Antonio Virgilio Failla, Anika Steffen, Theresia E B Stradal, Manuel Wolters, Martin Aepfelbacher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007527