Angiotensin II, a neuropeptide at the frontier between endocrinology and neuroscience: Is there a link between the angiotensin II type 2 receptor (AT2R) and Alzheimer’s disease?

Angiotensin II, a neuropeptide at the frontier between endocrinology and neuroscience: Is there a link between the angiotensin II type 2 receptor (AT2R) and Alzheimer’s disease?

Amyloid-β peptide deposition, abnormal hyperphosphorylation of tau, as well as inflammation and vascular damage, are associated with the development of Alzheimer’s disease. Angiotensin II (Ang II) is a peripheral hormone, as well as a neuropeptide, which binds two major receptors, namely the Ang II...

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Bibliographic Details
Main Authors: Nicole eGallo-Payet, Marie-Odile eGuimond, Lyne eBilodeau, Charlotta eWallinder, Mathias eAlterman, Anders eHallberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-08-01
Series:Frontiers in Endocrinology
Subjects:
Angiotensin II
Cognition
Vasodilation
Neuron
signaling
Alzheimer’s disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00017/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00017/full

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