Transcriptional regulation of PRKAR2B by miR-200b-3p/200c-3p and XBP1 in human prostate cancer

Transcriptional regulation of PRKAR2B by miR-200b-3p/200c-3p and XBP1 in human prostate cancer

The cyclic adenosine monophosphate (cAMP)-activated protein kinase A (PKA) pathway is profoundly implicated in Prostate cancer (PCa) progression. Previously, we showed that PRKAR2B, the type II-beta regulatory subunit of PKA, is highly expressed in castration-resistant prostate cancer (CRPC) and can...

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Bibliographic Details
Main Authors: Lei Xia, Qing Han, Chenfei Chi, Yinjie Zhu, Jiahua Pan, Baijun Dong, Yiran Huang, Weiliang Xia, Wei Xue, Jianjun Sha
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Prostate cancer
PRKAR2B
miR-200b-3p
miR-200c-3p
XBP1
Transcription factor
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220300536

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http://www.sciencedirect.com/science/article/pii/S0753332220300536

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