Development of a Monoclonal Antibody Against Porcine CD163 SRCR5 Domain Which Partially Blocks Infection of PRRSV

Development of a Monoclonal Antibody Against Porcine CD163 SRCR5 Domain Which Partially Blocks Infection of PRRSV

Porcine reproductive and respiratory syndrome virus (PRRSV), which seriously endangers the world pig industry, invades host cells through receptor-mediated endocytosis involving clathrin. CD163 is an essential receptor for PRRSV during its infection of cells. The scavenger receptor cysteine-rich 5 (...

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Bibliographic Details
Main Authors: Yujiao Zhang, Kuan Zhang, Hao Zheng, Changlong Liu, Yifeng Jiang, Nannan Du, Liwei Li, Guoxin Li, Lingxue Yu, Yanjun Zhou, Wu Tong, Kuan Zhao, Guangzhi Tong, Fei Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Veterinary Science
Subjects:
PRRSV
epitope
SRCR5
CD163
monoclonal antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.597843/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2020.597843/full

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