Phosphodiesterase-5 inhibitors: Raynaud's and beyond

Phosphodiesterase-5 inhibitors: Raynaud's and beyond

Phosphodiesterases (PDE) are a group of ubiquitously present enzymes involved in regulation of various cellular pathways. PDE5 acts to metabolize cyclic guanosine monophosphate (GMP). The various PDE5 inhibitors available are sildenafil, tadalafil, vardenafil, and mirodenafil. We shall discuss the r...

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Bibliographic Details
Main Authors: Sanat Phatak, Sajal Ajmani, Vikas Agarwal, Durga Prasanna Misra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Rheumatology
Subjects:
Fibrosis
phosphodiesterase 5 inhibitors
pulmonary hypertension
Raynaud's phenomenon
sildenafil
tadalafil
Online Access:http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=6;spage=227;epage=231;aulast=Phatak

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http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=6;spage=227;epage=231;aulast=Phatak

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