Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients

Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients

Adoptive cell therapy (ACT) using neoantigen-specific T cells can lead to tumor regression. Here the authors use an in vitro stimulation approach to isolate tumor specific memory T cells from peripheral blood of metastatic epithelial cancer patients targeting unique as well as shared mutations in th...

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Bibliographic Details
Main Authors: Gal Cafri, Rami Yossef, Anna Pasetto, Drew C. Deniger, Yong-Chen Lu, Maria Parkhurst, Jared J. Gartner, Li Jia, Satyajit Ray, Lien T. Ngo, Mohammad Jafferji, Abraham Sachs, Todd Prickett, Paul F. Robbins, Steven A. Rosenberg
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08304-z

Internet

https://doi.org/10.1038/s41467-019-08304-z

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