Alternative Okazaki Fragment Ligation Pathway by DNA Ligase III

Higher eukaryotes have three types of DNA ligases: DNA ligase 1 (Lig1), DNA ligase 3 (Lig3) and DNA ligase 4 (Lig4). While Lig1 and Lig4 are present in all eukaryotes from yeast to human, Lig3 appears sporadically in evolution and is uniformly present only in vertebrates. In the classical, textbook...

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Bibliographic Details
Main Authors: Hiroshi Arakawa, George Iliakis
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/6/2/385