Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells

Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells

Abstract Background Prostaglandin E2 (PGE2) is an endogenous lipid mediator of inflammation. Its production is regulated by the rate-limiting upstream enzyme cyclooxygenase-2 (COX-2). We have recently demonstrated that the major cell type expressing COX-2 in the germinal center is follicular dendrit...

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Bibliographic Details
Main Authors: Whajung Cho, Jongseon Choe
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Immunology
Subjects:
Follicular dendritic cell
Prostaglandin
Cyclooxygenase
MAPK
p38
Online Access:http://link.springer.com/article/10.1186/s12865-020-00347-y

Internet

http://link.springer.com/article/10.1186/s12865-020-00347-y

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