Systemic interleukin 10 levels indicate advanced stages while interleukin 17A levels correlate with reduced survival in esophageal adenocarcinomas.

INTRODUCTION:Reflux promotes esophageal adenocarcinomas (EAC) creating a chronic inflammatory environment. EAC show an increasing incidence in the Western World and median survival rates are still low. The main reasons for poor prognosis despite new multimodal therapies are diagnosis of EACs at an a...

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Main Authors: Karl-Frederick Karstens, Jan Kempski, Anastasios D Giannou, Erik Freiwald, Matthias Reeh, Michael Tachezy, Jakob R Izbicki, Ansgar W Lohse, Nicola Gagliani, Samuel Huber, Penelope Pelczar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231833