Automated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell line.

BACKGROUND:Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, represents a very important public health problem in Latin America where it is endemic. Although mostly asymptomatic at its initial stage, after the disease becomes chronic, about a third of the infected patients progress...

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Bibliographic Details
Main Authors: Julio Alonso-Padilla, Ignacio Cotillo, Jesús L Presa, Juan Cantizani, Imanol Peña, Ana I Bardera, Jose J Martín, Ana Rodriguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4304841?pdf=render