Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis

Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis

Abstract Background Canine visceral hemangiosarcoma (HSA) is a highly aggressive cancer of endothelial origin that closely resembles visceral angiosarcoma in humans, both clinically and histopathologically. Currently there is an unmet need for new diagnostics and therapies for both forms of this dis...

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Bibliographic Details
Main Authors: Chinatsu Mukai, Eunju Choi, Kelly L. Sams, Elena Zu Klampen, Lynne Anguish, Brooke A. Marks, Edward J. Rice, Zhong Wang, Lauren A. Choate, Shao-Pei Chou, Yukinari Kato, Andrew D. Miller, Charles G. Danko, Scott A. Coonrod
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Veterinary Research
Subjects:
Hemangiosarcoma
ChRO-seq
ECM
Collagen
LAMA4
PDPN
Online Access:http://link.springer.com/article/10.1186/s12917-020-02395-3

Internet

http://link.springer.com/article/10.1186/s12917-020-02395-3

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