Enhanced Expression of ABCB1 and Nrf2 in CD133-Positive Cancer Stem Cells Associates with Doxorubicin Resistance

The precise mechanism about drug resistance of cancer stem cells (CSCs) has not yet been completely understood. Based on the expression of CD44 and CD133, two well-recognized cell surface markers for CSC identification, we tried to separate HCT8 colorectal cancer cells into different subpopulations...

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Bibliographic Details
Main Authors: Shinji Goto, Tsuyoshi Kawabata, Tao-Sheng Li
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2020/8868849