Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer’s disease mouse models with abundant Aβ in plasma

Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer’s disease mouse models with abundant Aβ in plasma

Dietary or pharmacological manipulation of plasma lipids markedly influences amyloid deposition in animal models of Alzheimer’s Disease (AD). However, it is not known whether baseline plasma lipids in AD models differ from wild-type littermates throughout the natural history of disease. To address t...

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Bibliographic Details
Main Authors: Braydon L. Burgess, Sean A. McIsaac, Kathryn E. Naus, Jeniffer Y. Chan, Gavin H.K. Tansley, Jing Yang, Fudan Miao, Colin J.D. Ross, Miranda van Eck, Michael R. Hayden, William van Nostrand, Peter St. George-Hyslop, David Westaway, Cheryl L. Wellington
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Neurobiology of Disease
Subjects:
Triglyceride
Cholesterol
Very low density lipoprotein
Amyloid
Aβ
Alzheimer’s Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106001409

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http://www.sciencedirect.com/science/article/pii/S0969996106001409

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