Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis.
Francisella tularensis is a highly infectious bacterium causing the zoonotic disease tularemia. Its ability to multiply and survive in macrophages is critical for its virulence. By screening a bank of HimarFT transposon mutants of the F. tularensis live vaccine strain (LVS) to isolate intracellular...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2629122?pdf=render |