Randomised clinical trial investigating the specificity of a novel skin test (C-Tb) for diagnosis of M. tuberculosis infection.

Randomised clinical trial investigating the specificity of a novel skin test (C-Tb) for diagnosis of M. tuberculosis infection.

BACKGROUND: Tuberculin skin testing is simple and relatively inexpensive, but the specificity of PPD is affected by BCG vaccination. OBJECTIVE: Determine optimal dose and specificity of recombinant ESAT-6 and CFP-10 (C-Tb) produced in Lactococcus lactis for diagnosis of M. tuberculosis infection. ME...

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Bibliographic Details
Main Authors: Henrik Aggerbeck, Rafaela Giemza, Paulatsya Joshi, Pernille N Tingskov, Søren T Hoff, Julia Boyle, Peter Andersen, David J M Lewis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3653866?pdf=render

Internet

http://europepmc.org/articles/PMC3653866?pdf=render

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