One-Step Formation of Chondrocytes through Direct Reprogramming via Polysaccharide-Based Gene Delivery

An innovative strategy for the generation of chondrocytes was thoroughly studied in this paper. Polyetherimide-modified polysaccharides of Porphyra yezoensis (pmPPY) served as a nonviral gene vector and delivered Sox9 plasmid to directly reprogram mouse embryonic fibroblasts into chondrocytes. The g...

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Bibliographic Details
Main Authors: Qingtong Yu, Yan Wang, Xia Cao, Wenwen Deng, Michael Adu Frimpong, Jiangnan Yu, Ximing Xu
Format: Article
Language:English
Published: Hindawi-Wiley 2019-01-01
Series:Advances in Polymer Technology
Online Access:http://dx.doi.org/10.1155/2019/7632873