Targeting Human Mast Cells Expressing G-Protein-Coupled Receptors in Allergic Diseases

The G-protein-coupled receptors (GPCRs) are the largest known group of integral membrane receptor proteins and are the most common targets of pharmacotherapy. Mast cells (MCs) have been reported to play an important role in allergic diseases, such as urticaria and bronchial asthma. There is an incre...

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Bibliographic Details
Main Authors: Yoshimichi Okayama, Hirohisa Saito, Chisei Ra
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015307735