Normalizing for individual cell population context in the analysis of high-content cellular screens

<p>Abstract</p> <p>Background</p> <p>High-content, high-throughput RNA interference (RNAi) offers unprecedented possibilities to elucidate gene function and involvement in biological processes. Microscopy based screening allows phenotypic observations at the level of in...

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Bibliographic Details
Main Authors: Knapp Bettina, Rebhan Ilka, Kumar Anil, Matula Petr, Kiani Narsis A, Binder Marco, Erfle Holger, Rohr Karl, Eils Roland, Bartenschlager Ralf, Kaderali Lars
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/485