Aminoguanidine partially prevents the reduction in liver pyruvate kinase activity in diabetic rats

Background : Low molecular weight aldehydes and carbonyl compounds which are derived from glucose metabolism are prevalent in diabetic plasma. These compounds react to amino groups of Lys and Arg and lead to the formation of advanced glycation end products (AGEs). This modification changes the funct...

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Bibliographic Details
Main Authors: Alimohammad Amiri Majd, Mohammad Taghi Goodarzi, Taghi Hassanzadeh, Heidar Tavilani, Jamshid Karimi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Advanced Biomedical Research
Subjects:
rat
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=260;epage=260;aulast=Majd