Global Perspective on the Development of Genetically Modified Immune Cells for Cancer Therapy

Since the first genetically-engineered clinical trial was posted to clinicaltrials.gov in 2003 (NCT00019136), chimeric antigen receptor (CAR) and T-cell receptor (TCR) therapies have exhibited unprecedented growth. USA, China, and Europe have emerged as major sites of investigation as many new biote...

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Bibliographic Details
Main Authors: Laetitia Pinte, Amy Cunningham, Helene Trébéden-Negre, Sarah Nikiforow, Jerome Ritz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.608485/full