Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
<p>Abstract</p> <p>Background</p> <p>Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models assume the statistical independence of each position in the sequen...
Main Authors: | Webb-Robertson Bobbie-Jo, Bystroff Christopher |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/9/429 |
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