Targeting prominin2 transcription to overcome ferroptosis resistance in cancer
Abstract Understanding how cancer cells resist ferroptosis is a significant problem that impacts ongoing efforts to stimulate ferroptosis as a therapeutic strategy. We reported that prominin2 is induced by ferroptotic stimuli and functions to resist ferroptotic death. Although this finding has signi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-08-01
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Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.15252/emmm.202013792 |