Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum

Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum

Objective:The role of BDNF (brain-derived neurotrophic factor), CREB (cAMP response element binding) and VGF neuropeptide has been proved in antidepressant activity of long term saffron administration in the rat hippocampus. In this study we evaluated the role of these proteins in antidepressant act...

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Bibliographic Details
Main Authors: Najmeh Asrari, Rezvan Yazdian-Robati, Khalil Abnous, BiBi Marjan Razavi, Mrazieh Rashednia, Faezeh Vahdati Hasani, Hossein Hosseinzadeh
Format: Article
Language:English
Published: Korean Pharmacopuncture Institute 2018-03-01
Series:Journal of Pharmacopuncture
Subjects:
bdnf
creb
crocus sativus
depression
p-creb
vgf
cerebellum
Online Access:http://www.journal-pharm.com/sub/view/238

Internet

http://www.journal-pharm.com/sub/view/238

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