Lycopene Enhances Docetaxel's Effect in Castration-Resistant Prostate Cancer Associated with Insulin-like Growth Factor I Receptor Levels

Docetaxel is currently the most effective drug for the treatment of castration-resistant prostate cancer (CRPC), but it only extends life by an average of 2 months. Lycopene, an antioxidant phytochemical, has antitumor activity against prostate cancer (PCa) in several models and is generally safe....

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Bibliographic Details
Main Authors: Yaxiong Tang, Basmina Parmakhtiar, Anne R. Simoneau, Jun Xie, John Fruehauf, Michael Lilly, Xiaolin Zi
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800503