PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease
Abstract That certain cell types in the central nervous system are more likely to undergo neurodegeneration in Parkinson’s disease is a widely appreciated but poorly understood phenomenon. Many vulnerable subpopulations, including dopamine neurons in the substantia nigra pars compacta, have a shared...
Main Authors: | Preston Ge, Valina L. Dawson, Ted M. Dawson |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13024-020-00367-7 |
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