Targeting Phosphatidylserine on Apoptotic Cells with Phages and Peptides Selected from a Bacteriophage Display Library

Phosphatidylserine (PS) is a well-characterized biomarker for apoptosis. Ligands that bind to PS can be used for noninvasive imaging of therapy-induced cell death, particularly apoptosis. In this study, we screened a random 12-mer peptide phage library on liposomes prepared from PS. One clone displa...

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Bibliographic Details
Main Authors: Ruping Shao, Chiyi Xiong, Xiaoxia Wen, Juri G. Gelovani, Chun Li
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2007-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2007.00037