Organocatalytic Asymmetric Michael Addition in Aqueous Media by a Hydrogen-Bonding Catalyst and Application for Inhibitors of GABA<sub>B</sub> Receptor
Catalysts based on (<i>R</i>, <i>R</i>)-1,2-diphenylethylenediamine are, as chiral organic catalysts, applied to the asymmetric Michael addition to <i>α</i>, <i>β</i>-unsaturated nitroalkenes under neutral conditions. The role of an aqueous medium for...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-09-01
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| Series: | Catalysts |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4344/11/9/1134 |