Lacto-N-biose synthesis via a modular enzymatic cascade with ATP regeneration

Lacto-N-biose synthesis via a modular enzymatic cascade with ATP regeneration

Summary: Human milk oligosaccharides (HMOs), the third most abundant solid component of human milk, are reported to be beneficial to infant health. The biosynthesis of lacto-N-biose (LNB), the building block for HMOs, suffers from excessive addition of cofactors and intermediate inhibition. Here, we...

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Bibliographic Details
Main Authors: Zhiqiang Du, Zhengyao Liu, Yinshuang Tan, Kangle Niu, Wei Guo, Yangyang Jia, Xu Fang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Biological Sciences
Biotechnology
Biochemical Reactors
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002042

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http://www.sciencedirect.com/science/article/pii/S2589004221002042

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