Co-Crystal Structures of Furosemide:Urea and Carbamazepine:Indomethacin Determined from Powder X-Ray Diffraction Data

Co-Crystal Structures of Furosemide:Urea and Carbamazepine:Indomethacin Determined from Powder X-Ray Diffraction Data

Co-crystallization is a promising approach to improving both the solubility and the dissolution rate of active pharmaceutical ingredients. Crystal structure determination from powder diffraction data plays an important role in determining co-crystal structures, especially those generated by mechanoc...

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Bibliographic Details
Main Authors: Okba Al Rahal, Mridul Majumder, Mark J. Spillman, Jacco van de Streek, Kenneth Shankland
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Crystals
Subjects:
co-crystal
powder diffraction
global optimization
dft
pharmaceuticals
rietveld refinement
Online Access:https://www.mdpi.com/2073-4352/10/1/42

Internet

https://www.mdpi.com/2073-4352/10/1/42

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