Pretreatment of epithelial cells with live Streptococcus pneumoniae has no detectable effect on influenza A virus replication in vitro.

Influenza A virus (IAV) and Streptococcus pneumoniae (pneumococcus) are two major upper respiratory tract pathogens responsible for exacerbated disease in coinfected individuals. Despite several studies showing increased susceptibility to secondary bacterial infections following IAV infection, infor...

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Bibliographic Details
Main Authors: Kang Ouyang, Shireen A Woodiga, Varun Dwivedi, Carolyn M Buckwalter, Anirudh K Singh, Basavaraj Binjawadagi, Jagadish Hiremath, Cordelia Manickam, Rose Schleappi, Mahesh Khatri, Jianmin Wu, Samantha J King, Gourapura J Renukaradhya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940721?pdf=render