Insulin-sensitizing effects of vitamin D repletion mediated by adipocyte vitamin D receptor: Studies in humans and mice

Insulin-sensitizing effects of vitamin D repletion mediated by adipocyte vitamin D receptor: Studies in humans and mice

Objective: Adipose tissue inflammation and fibrosis appear to contribute to insulin resistance in obesity. Vitamin D receptor (Vdr) genes are expressed by adipocytes, macrophages, and fibroblasts, all of which could potentially play a role in adipose tissue inflammation and fibrosis. As vitamin D ha...

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Bibliographic Details
Main Authors: Eric Lontchi-Yimagou, Sona Kang, Akankasha Goyal, Kehao Zhang, Jee Y. You, Michelle Carey, Swati Jain, Shobhit Bhansali, Sylvia Kehlenbrink, Peng Guo, Evan D. Rosen, Preeti Kishore, Meredith Hawkins
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Metabolism
Subjects:
Vitamin D
Insulin sensitivity
Inflammation
Fibrosis
Adipocyte
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301691

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http://www.sciencedirect.com/science/article/pii/S2212877820301691

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