Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapse

Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapse

Anterior vaginal prolapse (AVP), the most common form of pelvic organ prolapse, has deleterious effects on women’s health. Here the authors employ single-cell RNA-seq to construct a transcriptomic atlas of vaginal wall cells from AVP patients, and find that extracellular matrix dysregulation and imm...

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Bibliographic Details
Main Authors: Yaqian Li, Qing-Yang Zhang, Bao-Fa Sun, Yidi Ma, Ye Zhang, Min Wang, Congcong Ma, Honghui Shi, Zhijing Sun, Juan Chen, Yun-Gui Yang, Lan Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20358-y

Internet

https://doi.org/10.1038/s41467-020-20358-y

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