Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice
We illustrate, through two case studies, that “mean-variance QTL mapping”—QTL mapping that models effects on the mean and the variance simultaneously—can discover QTL that traditional interval mapping cannot. Mean-variance QTL mapping is based on the double generalized linear model, which extends th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press
2018-12-01
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| Series: | G3: Genes, Genomes, Genetics |
| Subjects: | |
| Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.118.200194 |