Single-Cell Deconvolution of Head and Neck Squamous Cell Carcinoma

Single-Cell Deconvolution of Head and Neck Squamous Cell Carcinoma

Complexities in cell-type composition have rightfully led to skepticism and caution in the interpretation of bulk transcriptomic analyses. Recent studies have shown that deconvolution algorithms can be utilized to computationally estimate cell-type proportions from the gene expression data of bulk b...

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Bibliographic Details
Main Authors: Zongtai Qi, Yating Liu, Michael Mints, Riley Mullins, Reilly Sample, Travis Law, Thomas Barrett, Angela L. Mazul, Ryan S. Jackson, Stephen Y. Kang, Patrik Pipkorn, Anuraag S. Parikh, Itay Tirosh, Joseph Dougherty, Sidharth V. Puram
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
head and neck squamous cell carcinoma
deconvolution
single-cell RNA sequencing
regulatory T-cells
Online Access:https://www.mdpi.com/2072-6694/13/6/1230

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https://www.mdpi.com/2072-6694/13/6/1230

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