Post-Traumatic Sepsis Is Associated with Increased C5a and Decreased TAFI Levels

Background: Sepsis frequently occurs after major trauma and is closely associated with dysregulations in the inflammatory/complement and coagulation system. Thrombin-activatable fibrinolysis inhibitor (TAFI) plays a dual role as an anti-fibrinolytic and anti-inflammatory factor by downregulating com...

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Bibliographic Details
Main Authors: Jan Tilmann Vollrath, Ingo Marzi, Anna Herminghaus, Thomas Lustenberger, Borna Relja
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/9/4/1230