Tetracycline-Regulated Expression of VEGF-A in Beta Cells Induces Angiogenesis: Improvement of Engraftment following Transplantation

Early revascularization of pancreatic islet cells after transplantation is crucial for engraftment, and it has been suggested that vascular endothelial growth factor-A (VEGF-A) plays a significant role in this process. Although VEGF gene therapy can improve angiogenesis, uncontrolled VEGF secretion...

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Bibliographic Details
Main Authors: Zoltan Mathe, Philippe Dupraz, Chris Rinsch, Bernard Thorens, Domenico Bosco, Marie Zbinden, Philippe Morel, Thierry Berney, Michael S. Pepper
Format: Article
Language:English
Published: SAGE Publishing 2006-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000006783981675