Up-Regulation of microRNA* Strands by Their Target Transcripts

During microRNA (miRNA) biogenesis, one strand of a 21–23 nucleotide RNA duplex is preferentially selected for entry into an RNA-induced silencing complex (RISC). The other strand, known as the miRNA* species, is typically thought to be degraded. Previous studies have provided miRNA* selection model...

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Bibliographic Details
Main Authors: Heon-Jin Lee, Su-Hyung Hong, Sung-Min Kang, Ji-Woong Choi
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/7/13231