Effect of Elatol, Isolated from Red Seaweed Laurencia dendroidea, on Leishmania amazonensis

Effect of Elatol, Isolated from Red Seaweed Laurencia dendroidea, on Leishmania amazonensis

In the present study, we investigated the antileishmanial activity of sesquiterpene elatol, the major constituent of the Brazilian red seaweed Laurencia dendroidea (Hudson) J.V. Lamouroux, against L. amazonensis. Elatol after 72 h of treatment, showed an IC50 of 4.0 µM and 0.45 µM for promastigote a...

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Bibliographic Details
Main Authors: Celso Vataru Nakamura, Renato Crespo Pereira, Daniela Bueno Sudatti, Éverson Miguel Bianco, Benedito Prado Dias Filho, Tânia Ueda-Nakamura, Adriana Oliveira dos Santos, Phercyles Veiga-Santos
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Marine Drugs
Subjects:
antileishmanial activity
Leishmania amazonensis
Laurencia dendroidea
elatol
Online Access:http://www.mdpi.com/1660-3397/8/11/2733/

Internet

http://www.mdpi.com/1660-3397/8/11/2733/

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