Coexistence of TERT Promoter Mutations and the BRAF V600E Alteration and Its Impact on Histopathological Features of Papillary Thyroid Carcinoma in a Selected Series of Polish Patients

Coexistence of TERT Promoter Mutations and the BRAF V600E Alteration and Its Impact on Histopathological Features of Papillary Thyroid Carcinoma in a Selected Series of Polish Patients

TERT promoter (TERTp) mutations are important factors in papillary thyroid carcinomas (PTCs). They are associated with tumor aggressiveness, recurrence, and disease-specific mortality and their use in risk stratification of PTC patients has been proposed. In this study we investigated the prevalence...

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Bibliographic Details
Main Authors: Dagmara Rusinek, Aleksandra Pfeifer, Jolanta Krajewska, Malgorzata Oczko-Wojciechowska, Daria Handkiewicz-Junak, Agnieszka Pawlaczek, Jadwiga Zebracka-Gala, Malgorzata Kowalska, Renata Cyplinska, Ewa Zembala-Nozynska, Mykola Chekan, Ewa Chmielik, Aleksandra Kropinska, Roman Lamch, Beata Jurecka-Lubieniecka, Barbara Jarzab, Agnieszka Czarniecka
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
TERTp mutation
BRAF V600E
papillary thyroid cancer
Online Access:http://www.mdpi.com/1422-0067/19/9/2647

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http://www.mdpi.com/1422-0067/19/9/2647

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