Chronic renal failure induces cell death in rat hippocampal CA1 via upregulation of αCaMKII/NR2A synaptic complex and phosphorylated GluR1-containing AMPA receptor cascades
Background: N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methylisoxazole-4-propinoic acid (AMPA) receptors bound to postsynaptic density-95 (PSD-95) and α isoform of calcium/calmodulin-dependent protein kinase II (αCaMKII) is fundamentally involved in the regulation of working memory. The...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Korean Society of Nephrology
2014-09-01
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Series: | Kidney Research and Clinical Practice |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211913214000837 |